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The All-In Podcast delivers conversations worth having. Hosted by Chamath Palihapitiya, Jason Calacanis, David Sacks, and David Friedberg, the show features insider takes on business, technology, and society and interviews with the world's most influential thinkers.
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[  Latest Episode  ]
Anthropic S-1 Shocker, Greatest Business Ever? Google’s $500B Wipeout, Midterm Predictions
Anthropic’s S-1 makes the case that AI demand is still early, highly profitable and capable of creating enormous value across the compute stack. But can power, data centers and capital keep pace? The besties break down Anthropic’s economics, AI’s competition with government borrowing for liquidity, and Google’s $500 billion market-cap drop as investors question search advertising. Plus, the risks of an AI-driven economy and final midterm predictions.
[  10/29/2026  ]
Can just over 50 billion hours of continuous physiological data predict health problems before traditional testing? WHOOP CEO Will Ahmed joins Jason to unpack the subscription pivot that made retention and long-term member outcomes the priority. They discuss AI coaching, journaling and early illness detection, plus WHOOP’s push into the gray zone between wellness and medical care through blood pressure insights, ECG, lab integrations and its battles with the FDA.
[  10/23/2026  ]
Is AI spending creating durable productivity, or circulating within a concentrated startup economy? Nikesh Arora joins Jason, Chamath and Friedberg to debate enterprise adoption, open-source infrastructure, cyber defense, rogue agents and unresolved liability. Plus, France’s unrest, weak growth, integration failures and fiscal reality, and Trump’s second-half strategy.
[  10/21/2026  ]
How soon will quantum computing break today’s cryptography? Arvind Krishna and Nikesh Arora discuss the 2030 security deadline, post-quantum migration, frontier versus open-weight AI economics, cyber warfare and regulation. Plus, why vertical integration could consolidate software stacks while keeping companies accountable for what their systems produce.
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